Oral weight loss medication vs GLP-1s: Which is right for me?

The journey to achieving and maintaining a healthy weight can be challenging, and for many people, it goes beyond just diet and exercise. In recent years, the pharmaceutical industry has introduced various medications to assist in weight loss. Two popular options are oral weight loss medications and GLP-1 receptor agonists (GLP-1s). 

Let’s explore the key differences between these two approaches to help you make an informed decision about what might be right for you.

Oral weight loss medications

Oral weight loss medications are drugs designed to help you reduce your weight by affecting appetite, metabolism, or absorption of nutrients. These medications come in pill form and are typically taken orally, making them convenient for daily use. Some common examples of oral weight loss medications include phentermine and Orlistat.


Phentermine is a stimulant that works by suppressing appetite. It stimulates the release of neurotransmitters in the brain that control hunger. It’s often prescribed for short-term use and works best when combined with a healthy diet and regular exercise.


Orlistat works by preventing the absorption of dietary fats in the intestines, leading to reduced calorie intake. It’s available both over-the-counter and in prescription strength.

GLP-1 Iinjectable weight loss medications

GLP-1s are a newer class of medications that have shown promise in both managing type 2 diabetes and promoting weight loss. These drugs mimic the effects of GLP-1, a naturally occurring hormone that regulates blood sugar levels and appetite. By activating the GLP-1 receptors, they help control blood sugar and reduce body weight. They’re usually injected through a small pen, so may not be suitable for anyone with a fear of needles.

When deciding between oral weight loss medications and GLP-1 receptor agonists, a few factors should be considered:

  • GLP-1s have demonstrated higher efficacy in weight loss compared to many oral medications. However, individual responses can vary, and some people may see better results with oral options.
  • Some people may find it challenging to tolerate the side effects of GLP-1s, while others may prefer the convenience of oral medications.
  • People with a history of cardiovascular issues may need to be cautious with certain medications. Consulting with a healthcare professional is crucial to determine the safest option.

Choosing the right option for you

Choosing the right weight loss medication involves careful consideration of individual health factors, preferences, and goals. While both oral weight loss medications and GLP-1 receptor agonists offer viable options, consulting with a professional healthcare service is the best way to find the right choice for you. 

Looking for support on your weight loss journey? Start a consultation with Levity today:

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